Egg Intake and the Incidence of Alzheimer's Disease in the Adventist Health Study-2 Cohort Linked with Medicare Data - PubMed
This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!
Clipboard, Search History, and several other advanced features are temporarily unavailable.
Skip to main page content
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before<br>sharing sensitive information, make sure you’re on a federal<br>government site.
The site is secure.
The https:// ensures that you are connecting to the<br>official website and that any information you provide is encrypted<br>and transmitted securely.
Access keys<br>NCBI Homepage<br>MyNCBI Homepage<br>Main Content<br>Main Navigation
Search:
Search
Advanced
Clipboard
User Guide
Save
Email<br>Send to<br>Clipboard
My Bibliography<br>Collections<br>Citation manager
Display options
Display options
Format
Abstract
PubMed
PMID
Save citation to file
Format:
Summary (text)<br>PubMed<br>PMID<br>Abstract (text)<br>CSV
Create file
Cancel
Email citation
Email address has not been verified. Go to
My NCBI account settings
to confirm your email and then refresh this page.
To:
Subject:
\/]*" title="The following characters are not allowed in the Subject field: "&=<>/">
Body:
\/]*" title="The following characters are not allowed in the Body field: "&=<>/">
Format:
Summary<br>Summary (text)<br>Abstract<br>Abstract (text)
MeSH and other data
Send email
Cancel
Add to Collections
Create a new collection
Add to an existing collection
Name your collection:
\/]*" title="The following characters are not allowed in the Name field: "&=<>/"<br>maxlength="100"<br>data-ga-category="save_share"<br>data-ga-action="create_collection"<br>data-ga-label="non_favorties_collection">
Name must be less than 100 characters
Choose a collection:
Unable to load your collection due to an error
Please try again
Add
Cancel
Add to My Bibliography
My Bibliography
Unable to load your delegates due to an error
Please try again
Add
Cancel
Your saved search
Name of saved search:
\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
Search terms:
Test search terms
Would you like email updates of new search results?
Saved Search Alert Radio Buttons
Yes
No
Email:
(change)
Frequency:
Monthly<br>Weekly<br>Daily
Which day?
The first Sunday<br>The first Monday<br>The first Tuesday<br>The first Wednesday<br>The first Thursday<br>The first Friday<br>The first Saturday<br>The first day<br>The first weekday
Which day?
Sunday<br>Monday<br>Tuesday<br>Wednesday<br>Thursday<br>Friday<br>Saturday
Report format:
Summary<br>Summary (text)<br>Abstract<br>Abstract (text)<br>PubMed
Send at most:
1 item<br>5 items<br>10 items<br>20 items<br>50 items<br>100 items<br>200 items
Send even when there aren't any new results
Optional text in email:
Save
Cancel
Create a file for external citation management software
Create file
Cancel
Your RSS Feed
Name of RSS Feed:
\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
Number of items displayed:
10<br>15<br>20<br>50<br>100
Create RSS
Cancel
RSS Link
Copy
Full text links
Elsevier Science
Free PMC article
Full text links
Actions<br>CiteCollectionsAdd to Collections<br>Create a new collection<br>Add to an existing collection
Name your collection:<br>/]*" title="The following characters are not allowed in the Name field: "&=<>/"<br>maxlength="100"<br>data-ga-category="collections_button"<br>data-ga-action="create_collection"<br>data-ga-label="non_favorties_collection"><br>Name must be less than 100 characters
Choose a collection:
Unable to load your collection due to an error<br>Please try again
Add
Cancel
PermalinkPermalink<br>Copy
Display options<br>Display options
Format<br>AbstractPubMedPMID
Full text links<br>CiteDisplay options<br>Display options
Format<br>AbstractPubMedPMID
Abstract
Background:
A substantial knowledge gap remains regarding the relationship between modifiable dietary factors and Alzheimer's disease risk. Eggs are a source of key nutrients that support brain health.
Objectives:
The aim of this study was to investigate the association between egg consumption and the incidence of Alzheimer's disease.
Methods:
Data were drawn from the Adventist Health Study-2, a large, prospective cohort of United States Seventh-day Adventists, linked with Medicare records to identify Alzheimer's disease diagnosis. Diet and lifestyle factors were assessed using a validated food frequency questionnaire. Egg consumption was categorized by frequency, ranging from never/rarely to ≥5 times per week. The analytic sample included 39,498 participants (mean follow-up: 15.3 y), among whom 2858 developed Alzheimer's disease. Multivariable-adjusted Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs). Restricted cubic spline analysis was conducted using continuous egg intake (g/d).
Results:
Egg consumption was inversely associated with Alzheimer's disease risk. Compared with never/rarely...