Hi HN. I’m Jon.I have Long COVID. Five years and counting. Somewhere around year two I realized every trial I actually wanted to be in was a plane ride away, and I was too sick to fly. I’d watch new studies open, look at the location, and close the tab.I asked researchers I trust why decentralized trials weren’t the default. The answers are honest ones. Clinical research is a slow-moving field for good reasons. The people running trials are clinicians and biostatisticians, not tech founders. The regulatory framework was written for a world of paper case report forms and site visits, and it takes years for the guidance to catch up to what’s technically possible.Nobody expected a mass disabling event on the scale of Long COVID. The field is genuinely headed toward decentralized as the default, and the FDA’s 2024 DCT guidance and 2026 real-time trials pilot are real signals of that. But the platforms researchers have to choose from today still cost six figures per study and still require physical sites. So most of the researchers I know use spreadsheets instead.So I built TrialPilot with two engineers I’ve worked with for a decade. The whole study runs from a patient’s phone. Researchers configure a study, generate a code, and watch enrollment in real time. Patients scan the code, sign consent on the phone, connect a wearable, and the study runs itself. Real functional tests like the six minute walk and NASA Lean Test happen from your living room instead of a clinic.Beachhead is invisible illness. Long COVID, ME/CFS, POTS, Lyme. The populations that get under measured because their symptoms don’t show up on a scheduled clinic visit, and get structurally excluded from research because they’re too sick to travel to it.We have clinical trial partners lined up and are getting ready to launch our first pilot studies. We’re also competing in the HHS TOPx Tech Sprint for AI and Invisible Illness, so wish us luck.https://www.trialpilot.app/Would love your impressions and feedback. What lands, what doesn’t, what would you build differently, what would make you use it or trust it.Especially from anyone who’s tried to run a trial and lost their weekends to it, or anyone who’s tried to enroll in one and lost their patience.I’ve been waiting five years for this to exist, so I built it.