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Never Miss a Breakthrough<br>Your most relevant papers across any scientific discipline, delivered directly to your inbox.<br>Get StartedHow It Works<br>By creating a free account, you’ll receive one daily email of paper matches based on your research profile. One-click unsubscribe in every email. See our Privacy Policy and Terms of Service.
NatureComputational Biology<br>Atomically accurate de novo design of antibodies with RFdiffusion<br>Bennett NR, Watson JL, Ragotte RJ et al.<br>Nov 2025
Astrophysical Journal LettersAstrophysics<br>Confirmation of a Runaway Supermassive Black Hole via its Supersonic Bow Shock<br>van Dokkum P, Jennings C, Pasha I et al.<br>Dec 2025
Nature PhysicsQuantum Physics<br>Neutron scattering and thermodynamic evidence for emergent photons and fractionalization in a pyrochlore spin ice<br>Gao B, Desrochers F, Tam DW et al.<br>Jun 2025
CAR-T ImmunotherapyQuantum Error CorrectionCRISPR Gene EditingDark Matter DetectionPerovskite Solar CellsOcean AcidificationProtein Language ModelsSolid-State BatteriesTwisted Bilayer GrapheneVolcanic ForecastingAlgorithmic FairnessBehavioral EconomicsMycorrhizal NetworksDeep-Sea BioluminescenceComputational ArchaeologyCAR-T ImmunotherapyQuantum Error CorrectionCRISPR Gene EditingDark Matter DetectionPerovskite Solar CellsOcean AcidificationProtein Language ModelsSolid-State BatteriesTwisted Bilayer GrapheneVolcanic ForecastingAlgorithmic FairnessBehavioral EconomicsMycorrhizal NetworksDeep-Sea BioluminescenceComputational ArchaeologyCAR-T ImmunotherapyQuantum Error CorrectionCRISPR Gene EditingDark Matter DetectionPerovskite Solar CellsOcean AcidificationProtein Language ModelsSolid-State BatteriesTwisted Bilayer GrapheneVolcanic ForecastingAlgorithmic FairnessBehavioral EconomicsMycorrhizal NetworksDeep-Sea BioluminescenceComputational Archaeology
Stay current, effortlessly<br>Set up once. The most relevant papers arrive every morning.
01<br>Describe your research<br>Write your project description in your own words: a hypothesis, a few sentences about your focus, or a full abstract. Just describe what you’re working on.
Research Project<br>CAR-T Cell Immunotherapy
Engineering next-generation CAR-T cells to overcome solid tumor resistance. Focused on improving antigen sensitivity, tumor microenvironment remodeling, and T cell persistence.
Evaluated papers<br>Sensitive CAR T cells redefine targetable CD70 expression in solid tumors<br>Science
Engineering CAR T cells to secrete VEGF-neutralizing scFvs enhances antitumor activity against solid tumors<br>Sci Transl Med
CAR T cells and T cell engagers for autoimmunity—lessons from hematology<br>Bone Marrow Transplantation
02<br>Matched to your work<br>Every day, new papers from across science are searched and scored against your research. Only the top papers make the cut.
03<br>Your research digest<br>Your top papers arrive every morning, selected for your specific research. Each one comes with a focused summary of the actual finding.
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7:00 AM
Your Research Digest
Preclinical CAR T study in mouse models of pancreatic, kidney, and ovarian cancer testing a high-sensitivity CD70-targeting HLA-independent T cell receptor...<br>Sensitive CAR T cells redefine targetable CD70 expression in solid tumors<br>Science · Read paper →
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See what you'd receive<br>A real digest for one research project, delivered to your inbox.
Daily Research Digest · Jul 23, 2026
Hi Alex,<br>Selected from 87,432 papers in the last 14 days.<br>Preclinical CAR T study in mouse models of pancreatic, kidney, and ovarian cancer testing a high-sensitivity CD70-targeting HLA-independent T cell receptor co-expressing CD80 and 4-1BBL. Demonstrates that heterogeneous, epigenetically regulated CD70 expression undetectable by conventional staining can be eliminated by these sensitive receptors, rescuing tumors that evade prototypic CAR T cells.<br>Sensitive CAR T cells redefine targetable CD70 expression in solid tumors<br>Hanina SA, Park T, Lopez M et al. · Feb 2026 · Science<br>Read paper →
Preclinical study in mouse models of glioblastoma and ovarian cancer testing CAR T cells engineered to secrete an anti-VEGF single-chain variable fragment. Shows the secretion approach yields complete tumor elimination in 63 to 88% of glioblastoma mice versus 0 to 38% for conventional CAR T or CAR T combined with systemic anti-VEGF antibody.<br>Engineering CAR T cells to secrete VEGF-neutralizing scFvs enhances antitumor activity against solid tumors<br>Gao TA, Shih RM, Clubb JD et al. · Mar 2026 · Science Translational Medicine<br>Read paper →
Narrative review synthesizing hematologic CAR T cell and T cell engager experience for application to...