Hubris in the Age of Intelligent Medicine

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Hubris in the age of intelligent medicine—from clinical hierarchies to algorithmic amplification - PMC

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NPJ Digit Med<br>. 2026 May 7;9:538. doi: 10.1038/s41746-026-02717-z

Hubris in the age of intelligent medicine—from clinical hierarchies to algorithmic amplification

Milit S Patel<br>Milit S Patel

1Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX USA

2Laboratory for Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA USA

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1,2, David Scales<br>David Scales

3Department of Medicine, Weill Cornell Medical College, New York, NY USA

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3, Janan Arslan<br>Janan Arslan

4Sorbonne Université, Institut du Cerveau—Paris Brain Institute—ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France

5Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC Australia

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4,5, Paola Pedrelli<br>Paola Pedrelli

6Department of Psychiatry, Massachusetts General Hospital, Boston, MA USA

7Department of Psychiatry, Harvard Medical School, Boston, MA USA

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6,7, Matthew G Crowson<br>Matthew G Crowson

8Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, MA USA

9Department of Otolaryngology-Head & Neck Surgery, Mass General Brigham, Boston, MA USA

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8,9, Rawan Abulibdeh<br>Rawan Abulibdeh

10TRANSFORM HF, Department of Cardiology, University Health Network, Toronto, ON Canada

11Peter Munk Cardiac Centre, University Health Network, Toronto, ON Canada

12Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON Canada

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10,11,12, Leo Anthony Celi<br>Leo Anthony Celi

2Laboratory for Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA USA

13Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA

14Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA USA

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2,13,14,✉

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1Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX USA

2Laboratory for Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA USA

3Department of Medicine, Weill Cornell Medical College, New York, NY USA

4Sorbonne Université, Institut du Cerveau—Paris Brain Institute—ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France

5Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC Australia

6Department of Psychiatry, Massachusetts General Hospital, Boston, MA USA

7Department of Psychiatry, Harvard Medical School, Boston, MA USA

8Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, MA USA

9Department of Otolaryngology-Head & Neck Surgery, Mass General Brigham, Boston, MA USA

10TRANSFORM HF, Department of Cardiology, University Health Network, Toronto, ON Canada

11Peter Munk Cardiac Centre, University Health Network, Toronto, ON Canada

12Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON Canada

13Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA USA

14Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA USA

✉Corresponding author.

Received 2026 Feb 8; Accepted 2026 Apr 27; Collection date 2026.

© The Author(s) 2026

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless...

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